SLC25A51 impacts drug sensitivity in AML cells by sustaining mitochondrial oxidative flux
M.-J. Lu, J. Busquets, V. Impedovo, Y.-T. Chang, W. Matsui, S. Tiziani, X. A. Cambronne
This study shows that SLC25A51 sustains mitochondrial oxidative flux in AML, leading to drug sensitivity when inhibited, especially with glutaminase inhibitors.
bioRxiv · Nov 15, 2022 · PreprintCancer Biology