Author

J. C. Horowitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

R. K. Mallampalli· 3 shared C. Carlin· 2 shared D. Jones· 2 shared E. M. Oltz· 2 shared J. S. Bednash· 2 shared L. J. Saif· 2 shared R. J. Gumina· 2 shared S.-L. Liu· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

R. K. Mallampalli

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Author profile →

3 papers

Recent·Most cited

Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion

P. Li, Y. Liu, J. Faraone, C. C. Hsu, M. Chamblee, Y.-M. Zheng, C. Carlin, J. S. Bednash, J. C. Horowitz, R. K. Mallampalli, L. J. Saif, E. M. Oltz, D. Jones, J. Li, R. J. Gumina, S.-L. Liu

This study compares immune evasion, antigenicity, and cell-cell fusion properties of SARS-CoV-2 BA.2.87.1 and JN.1 variants, finding BA.2.87.1 shows less neutralization escape and higher infectivity than JN.1 and XBB.1.5.

bioRxiv · Mar 11, 2024Microbiology

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

B. Piper, S. Bogamuwa, T. Hossain, D. Farkas, L. Rosas, A. Green, G. Newcomb, N. Sun, J. C. Horowitz, A. R. Bhagwani, H. Yang, T. V. Kudryashova, M. Rojas, A. L. Mora, P. Yan, , L. Farkas

This study shows RAB7 deficiency impairs endothelial function and causes pulmonary hypertension in mice, with potential for RAB7 activation as a therapeutic strategy.

Journal of Clinical Investigation · Feb 1, 2024Peer-reviewedPhysiology

Immune Evasion, Infectivity, and Fusogenicity of SARS-CoV-2 Omicron BA.2.86 and FLip Variants

P. Qu, K. Xu, J. N. Faraone, N. Goodarzi, Y.-M. Zheng, C. Carlin, J. S. Bednash, J. C. Horowitz, R. K. Mallampalli, L. J. Saif, E. M. Oltz, D. Jones, R. J. Gumina, S.-L. Liu

This study compares immune evasion, infectivity, and fusogenicity of SARS-CoV-2 variants BA.2.86 and FLip using neutralization assays and cell-based experiments.

bioRxiv · Sep 11, 2023Microbiology