Author

J. C. Jacob

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Pharmacology & Toxicology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Khan· 1 shared H. I. Akbarali· 1 shared I. Alam· 1 shared K. H. Muchhala· 1 shared M. Kang· 1 shared S. Hasan· 1 shared W. L. Dewey· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Khan

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1 paper

Recent·Most cited

Rapid tolerance to morphine in the myenteric neurons of the small intestine is independent of β-arrestin-2 and mediated by PKC

K. H. Muchhala, J. C. Jacob, I. Alam, S. Hasan, A. Khan, M. Kang, W. L. Dewey, H. I. Akbarali

This study shows that morphine tolerance in the small intestine develops rapidly and is independent of β-arrestin-2 but mediated by PKC, unlike peripheral antinociceptive tolerance.

bioRxiv · Jul 17, 2020 · PreprintPharmacology & Toxicology