Author

J. C. Newton

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Acharya· 1 shared E. Skeens· 1 shared G. Jogl· 1 shared G. P. Lisi· 1 shared G. Palermo· 1 shared K. W. East· 1 shared U. N. Morzan· 1 shared V. S. Batista· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

A. Acharya

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1 paper

Recent·Most cited

Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics

K. W. East, J. C. Newton, U. N. Morzan, A. Acharya, E. Skeens, G. Jogl, V. S. Batista, G. Palermo, G. P. Lisi

This study uses NMR and GaMD simulations to investigate allosteric motions in the CRISPR-Cas9 HNH nuclease, revealing a dynamic pathway involved in DNA cleavage activation.

bioRxiv · Oct 10, 2019Biophysics