Author

U. N. Morzan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

G. P. Lisi· 2 shared G. Palermo· 2 shared K. W. East· 2 shared V. S. Batista· 2 shared A. Acharya· 1 shared E. Skeens· 1 shared G. Jogl· 1 shared J. C. Newton· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

G. P. Lisi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Enhanced Specificity Mutations Perturb Allosteric Signaling in CRISPR-Cas9

G. Palermo, L. Nierzwicki, K. W. East, U. N. Morzan, P. R. Arantes, G. P. Lisi, V. S. Batista

The paper investigates how specificity-enhancing mutations in CRISPR-Cas9 affect allosteric signaling, showing that mutations like K855A disrupt the HNH domain structure and signaling transfer more than others.

bioRxiv · Sep 14, 2021Biophysics

Allosteric Motions of the CRISPR-Cas9 HNH Nuclease Probed by NMR and Molecular Dynamics

K. W. East, J. C. Newton, U. N. Morzan, A. Acharya, E. Skeens, G. Jogl, V. S. Batista, G. Palermo, G. P. Lisi

This study uses NMR and GaMD simulations to investigate allosteric motions in the CRISPR-Cas9 HNH nuclease, revealing a dynamic pathway involved in DNA cleavage activation.

bioRxiv · Oct 10, 2019Biophysics