Author

J. C. Setubal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

J. P. Gogarten· 2 shared L. T. Rangel· 2 shared A. Cuba Portocarrero· 1 shared A. Guerra Santa Cruz· 1 shared A. M. da Silva· 1 shared C. Monge Pimentel· 1 shared C. Morais Piroupo· 1 shared C. S. Farah· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersEvolutionary Biology

J. P. Gogarten

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Author profile →

4 papers

Recent·Most cited

Isolation of a Bacillus safensis from mine tailings in Peru, genomic characterization and characterization of its cyanide- degrading enzyme CynD

S. Justo Arevalo, D. Zapata Sifuentes, A. Cuba Portocarrero, M. Brescia Reategui, C. Monge Pimentel, L. Farage Martins, P. Marques Pierry, C. Morais Piroupo, A. Guerra Santa Cruz, M. Quinones Aguilar, C. S. Farah, J. C. Setubal, A. M. da Silva

The paper isolates a Bacillus safensis strain from mine tailings and characterizes its cyanide-degrading enzyme CynD, showing its activity at high pH and strong induction by cyanide.

bioRxiv · Nov 27, 2021Microbiology

Plasmodium falciparum Acetyl-CoA Synthetase is essential for parasite intraerythrocytic development and chromatin modification

I. O. Prata, E. F. Galindo Cubillos, D. Barbosa, J. Martins, J. C. Setubal, G. Wunderlich

This study shows that PfACS is essential for Plasmodium falciparum growth and chromatin regulation, with knockdown or inhibition impairing parasite development and altering histone acetylation.

bioRxiv · Jun 13, 2021Microbiology

Non-phylogenetic identification of co-evolving genes for reconstructing the archaeal Tree of Life

L. T. Rangel, S. M. Soucy, J. C. Setubal, J. P. Gogarten, G. P. Fournier

This paper introduces the Evolutionary Similarity Index (IES) to identify co-evolving gene families in archaea, finding eight major clusters with compatible evolutionary trends and evidence of horizontal gene transfer.

bioRxiv · Oct 16, 2020 · PreprintEvolutionary Biology

Identification and characterization of putative Aeromonas spp. T3SS effectors

L. T. Rangel, J. Marden, S. Colston, J. C. Setubal, J. Graf, J. P. Gogarten

This study identifies and validates T3SS effector proteins in Aeromonas spp. using a bioinformatics pipeline and experimental validation in yeast, finding 21 effector groups with 15 showing cytotoxicity.

bioRxiv · Mar 7, 2019Microbiology