Author

J. C. Sivils

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

B. Tait· 1 shared C. Dickey· 1 shared D. Culbertson· 1 shared D. M. Hutt· 1 shared J. E. Gestwicki· 1 shared J. H. Dyson· 1 shared J. K. Singh· 1 shared M. B. Cox· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

B. Tait

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1 paper

Recent·Most cited

Management of Hsp90-Dependent Protein Folding by Small Molecule Targeting the Aha1 Co-Chaperone

J. K. Singh, B. Tait, N. Guy, J. C. Sivils, D. Culbertson, C. Dickey, S. Y. Kuo, J. E. Gestwicki, D. M. Hutt, J. H. Dyson, M. B. Cox, W. E. Balch

This study identifies SEW04784, a small molecule that disrupts Aha1-stimulated Hsp90 ATPase activity, showing therapeutic potential in prostate cancer and tauopathies without affecting basal Hsp90 function.

bioRxiv · Sep 11, 2018Biochemistry