Author

J. C. T. Eijkel

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Biochemistry· 1

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Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Approach:wet-lab / biochemical assay· 1

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J. E. van Dongen· 1 shared J. T. W. Berendsen· 1 shared L. I. Segerink· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBiochemistry

J. E. van Dongen

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BiochemistrybioRxivApr 6, 2021

A CRISPR/Cas12a-assisted platform for identification and quantification of single CpG methylation sites

J. E. van Dongen, J. T. W. Berendsen, J. C. T. Eijkel, L. I. Segerink

This paper introduces a CRISPR/Cas12a-based method to detect and quantify single CpG methylation sites using methylation-sensitive restriction enzymes, demonstrating its application in cancer gene analysis.

DOI 10.1016/j.bios.2021.113624

DNA methylationexperimental assay

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