Author

J. C. Valdoz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

G. Raghu· 2 shared M. L. Vallecillo-Zuniga· 2 shared P. D. Poulson· 2 shared P. M. Van Ry· 2 shared A. Chang· 1 shared A. Fernandez· 1 shared A. K. Bera· 1 shared A. Olshefsky· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

G. Raghu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

A. Roy, L. Shi, A. Chang, X. Dong, A. Fernandez, J. C. Kraft, J. Li, V. Q. Le, R. V. Winegar, G. M. Cherf, D. Slocum, P. D. Poulson, G. E. casper, M. L. Vallecillo-Zuniga, J. C. Valdoz, , D. Baker

This paper designs highly selective miniprotein inhibitors for integrins αvβ6 and αvβ8 with picomolar affinity and therapeutic potential in a mouse fibrosis model.

bioRxiv · Jun 12, 2023 · PreprintBiochemistry

Soluble ECM promotes organotypic formation in lung alveolar model

J. C. Valdoz, N. A. Franks, C. G. Cribbs, D. J. Jacobs, E. L. Dodson, C. J. Knight, P. D. Poulson, S. R. Garfield, B. C. Johnson, B. M. Hemeyer, M. T. Sudo, J. A. Saunooke, B. C. Kartchner, A. Saxton, M. L. Vallecillo-Zuniga, , P. M. Van Ry

This study shows that adding soluble ECM to suspension culture enables the formation of organotypic lung structures from stable cell lines, including lumen-like airspaces and vasculature, and models lung fibrosis with drug testing capabilities.

bioRxiv · Sep 16, 2021Bioengineering