Author

G. M. Cherf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:deep learning· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Chang· 1 shared A. Fernandez· 1 shared A. J. Giaccia· 1 shared A. K. Bera· 1 shared A. N. Diep· 1 shared A. Olshefsky· 1 shared A. Roy· 1 shared B. Wei· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Chang

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Author profile →

2 papers

Recent·Most cited

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

A. Roy, L. Shi, A. Chang, X. Dong, A. Fernandez, J. C. Kraft, J. Li, V. Q. Le, R. V. Winegar, G. M. Cherf, D. Slocum, P. D. Poulson, G. E. casper, M. L. Vallecillo-Zuniga, J. C. Valdoz, , D. Baker

This paper designs highly selective miniprotein inhibitors for integrins αvβ6 and αvβ8 with picomolar affinity and therapeutic potential in a mouse fibrosis model.

bioRxiv · Jun 12, 2023 · PreprintBiochemistry

Neutralizing PD-L1 and PD-L2 Enhances the Efficacy of Immune Checkpoint Inhibitors in Ovarian Cancer.

Y. R. Miao, K. N. Thakkar, J. Qian, M. S. Kariolis, W. Huang, S. A. Nandagopal, T. Yang, A. N. Diep, G. M. Cherf, Y. Xu, E. J. Moon, Y. Xiao, H. Alemany, T. Li, W. Yu, , A. J. Giaccia

The paper develops a high-affinity sPD-1 decoy molecule that neutralizes both PD-L1 and PD-L2, showing superior antitumor activity in ovarian cancer models compared to PD-1/PD-L1 antibodies.

bioRxiv · Jan 19, 2020 · PreprintCancer Biology