Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S. Basu, O. Shukron, D. Hall, P. Parruto, A. Ponjavic, D. Shah, W. Boucher, D. Lando, W. Zhang, N. Reynolds, L. H. Sober, A. Jartseva, R. Ragheb, X. Ma, J. Cramard, , E. D. Laue
This study uses live-cell 3D single-molecule tracking to show that the NuRD complex decompacts chromatin and alters enhancer dynamics by increasing their movement and reducing time in a fast-diffusing state.
bioRxiv · Apr 3, 2020 · PreprintCell Biology