Author

N. Reynolds

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Aubert· 1 shared A. Carr· 1 shared A. Dubois· 1 shared A. Filby· 1 shared A. Husain· 1 shared A. Jartseva· 1 shared A. Ponjavic· 1 shared A.-C. Villani· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A. Aubert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Repurposing clemastine to target glioblastoma cell stemness

M. A. Sun, R. Yang, H. Liu, W. Wang, X. Song, B. Hu, N. Reynolds, K. Roso, L. H. Chen, P. K. Greer, S. T. Keir, R. E. McLendon, S.-Y. Cheng, D. D. Bigner, D. M. Ashley, , Y. He

This study shows clemastine, an antihistamine, reduces glioblastoma stemness by targeting EBP, a cholesterol pathway enzyme, and promotes differentiation of oligodendrocyte progenitor cells.

bioRxiv · Nov 5, 2022 · PreprintCancer Biology

Poised cell circuits in human skin are activated in disease

G. Reynolds, P. Vegh, J. Fletcher, E. Poyner, E. Stephenson, I. Goh, R. Botting, N. Huang, B. Olabi, A. Dubois, D. Dixon, K. Green, D. Maunder, J. Engelbert, M. Efremova, , F. Watt

The paper creates a single-cell atlas of human skin, showing how cell circuits change in inflammatory diseases like atopic dermatitis and psoriasis.

bioRxiv · Nov 5, 2020 · PreprintImmunology

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S. Basu, O. Shukron, D. Hall, P. Parruto, A. Ponjavic, D. Shah, W. Boucher, D. Lando, W. Zhang, N. Reynolds, L. H. Sober, A. Jartseva, R. Ragheb, X. Ma, J. Cramard, , E. D. Laue

This study uses live-cell 3D single-molecule tracking to show that the NuRD complex decompacts chromatin and alters enhancer dynamics by increasing their movement and reducing time in a fast-diffusing state.

bioRxiv · Apr 3, 2020 · PreprintCell Biology