Author

J. D. Caballero

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Evolutionary Biology· 1

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Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

C. MacLean· 1 shared L. Ogunlana· 1 shared L. P. Shaw· 1 shared P. K. Jangir· 1 shared Q. Yang· 1 shared R. M. Wheatley· 1 shared T. R. Walsh· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

C. MacLean

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1 paper

Recent·Most cited

Pre-existing chromosomal polymorphisms in pathogenic E. coli potentiate the evolution of antibiotic resistance by MCR-1 plasmid acquisition

P. K. Jangir, Q. Yang, L. P. Shaw, J. D. Caballero, L. Ogunlana, R. M. Wheatley, T. R. Walsh, C. MacLean

The paper shows pre-existing lpxC polymorphisms in E. coli enhance the evolution of colistin resistance via MCR-1 plasmid acquisition through positive epistasis.

bioRxiv · Feb 20, 2022 · PreprintEvolutionary Biology