Author

J. D. Lightfoot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:fungi (other)· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Assay:imaging· 1

Frequent Co-Authors

E. M. Adams· 3 shared B. L. Wells· 2 shared K. K. Fuller· 2 shared M. M. Kamath· 2 shared A. Rokas· 1 shared E. A. Hatmaker· 1 shared G. H. Goldman· 1 shared H. A. Raja· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersPathology

E. M. Adams

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aspergillus fumigatus hypoxia adaptation is critical for the establishment of fungal keratitis.

J. D. Lightfoot, E. M. Adams, M. M. Kamath, B. L. Wells, K. K. Fuller

This study shows that hypoxia adaptation in Aspergillus fumigatus is essential for fungal keratitis, as a hypoxia-sensitive mutant failed to establish infection.

bioRxiv · Oct 1, 2023 · PreprintPathology

Basal UPR activity in Aspergillus fumigatus regulates adaptation to nutrient stress and is critical for the establishment of corneal infection

M. M. Kamath, J. D. Lightfoot, E. M. Adams, B. L. Wells, K. K. Fuller

This paper shows that the UPR pathway in Aspergillus fumigatus is essential for corneal infection despite not being highly activated in the host environment, and suggests it could be a target for antifungals.

bioRxiv · May 22, 2023 · PreprintMicrobiology

Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its non-pathogenic close relatives

E. A. Hatmaker, M. Rangel-Grimaldo, H. A. Raja, S. L. Knowles, H. Pourhadi, K. Fuller, E. M. Adams, J. D. Lightfoot, R. Bastos, G. H. Goldman, N. H. Oberlies, A. Rokas

This study compares genomic and phenotypic traits of Aspergillus flavus and its non-pathogenic relatives to understand pathogenicity evolution.

bioRxiv · Jul 12, 2022 · PreprintEvolutionary Biology