G. H. Goldman

The paper identifies conidial surface proteins in Aspergillus fumigatus and shows their role in immune evasion during infection.

This study examines the evolution of the gliotoxin biosynthetic gene cluster in Penicillium fungi across 35 genomes, finding conserved resistance genes and fragmented BGCs in most species.

This study analyzes 11 Aspergillus fumigatus isolates from COVID-19 patients with pulmonary aspergillosis, finding genomic diversity but similar stress responses to infection.

The paper uses genome-scale phylogenomics to analyze 711 Aspergillus genomes, revealing taxonomic issues and strain misidentifications.

This study compares genomic and phenotypic traits of Aspergillus flavus and its non-pathogenic relatives to understand pathogenicity evolution.

This study shows that FhdA regulates mitochondrial activity and tRNA expression in Aspergillus fumigatus during caspofungin tolerance.

This study shows that some Aspergillus fumigatus isolates can persist in the presence of voriconazole, a fungicidal drug, and this persistence is associated with a distinct transcriptional profile and reduced treatment efficacy.

This study identifies secondary metabolites produced by Aspergillus fumigatus and Pseudomonas aeruginosa during biofilm formation in normoxia and hypoxia, revealing differences in metabolite secretion between monoculture and co-culture.

The paper investigates whether caspofungin tolerance in Aspergillus fumigatus is a population-level or individual-level trait by testing conidia from clinical isolates.

This study identifies conserved transcription factors and genes involved in gliotoxin protection in Aspergillus species through RNA-sequencing and deletion screening.

This study investigates transcriptional heterogeneity in Aspergillus fumigatus strains responding to caspofungin, identifying a core response and variable response linked to secondary metabolite biosynthesis and iron homeostasis.

This paper investigates how acetate utilization by Aspergillus fumigatus affects virulence traits and pathogenicity, showing its role in secondary metabolite secretion, cell wall composition, and in vivo virulence.

This study screens 1,127 compounds against Aspergillus fumigatus, identifies miltefosine as fungicidal, and reveals RmiA as a transcription factor regulating sphingolipid biosynthesis involved in miltefosine resistance.

This paper investigates the role of GprM and GprJ GPCRs in A. fumigatus, showing they regulate cell wall integrity, secondary metabolite production, and virulence.

The paper compares secondary metabolite profiles and biosynthetic gene clusters between the pathogenic Aspergillus fumigatus and its nonpathogenic relatives A. fischeri and A. oerlinghausenensis, identifying conserved and diverged virulence-associated traits.

The paper characterizes the virulence and drug susceptibility of clinical isolates of Aspergillus fumigatus, A. lentulus, and A. fumigatiaffinis, revealing genomic and phenotypic heterogeneity across species and strains.

This study shows that the non-pathogenic Aspergillus fischeri produces gliotoxin like the pathogenic A. fumigatus, but losing secondary metabolite production does not affect its virulence.

This study characterizes two clinical isolates of A. nidulans, showing differences in growth, metabolism, stress response, and virulence compared to a reference strain.

This study compares Aspergillus fischeri and Aspergillus fumigatus to understand differences in pathogenicity, finding A. fischeri is less virulent, grows slower under stress, and has divergent secondary metabolism.