Author

R. Bastos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:fungi (other)· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. C. Colabardini· 3 shared G. H. Goldman· 3 shared T. F. dos Reis· 3 shared A. Rokas· 2 shared G. Goldman· 2 shared H. A. Raja· 2 shared N. H. Oberlies· 2 shared P. A. de Castro· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMicrobiology

A. C. Colabardini

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolutionary origin, population diversity, and diagnostics for a cryptic hybrid pathogen

J. L. Steenwyk, S. L. Knowles, R. Bastos, C. Balamurugan, D. Rinker, M. E. Mead, C. D. Roberts, H. A. Raja, Y. Li, A. C. Colabardini, P. A. Castro, T. F. Reis, D. Canovas, R. L. Sanchez, K. Lagrou, , A. Rokas

This study identifies and characterizes the cryptic fungal pathogen Aspergillus latus, revealing its hybrid origin and developing genomic and phenotypic markers for accurate diagnosis.

bioRxiv · Jul 3, 2023 · PreprintEvolutionary Biology

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi

T. F. dos Reis, P. A. de Castro, R. Bastos, C. F. Pinzan, P. F. Souza, S. Ackloo, M. A. Hossain, D. Drewry, S. Alkhazraji, A. Ibrahim, H. Jo, W. F. deGrado, G. Goldman

This study identifies brilacidin as a compound that enhances the antifungal activity of caspofungin against multiple human pathogenic fungi, including overcoming resistance mechanisms.

bioRxiv · Sep 28, 2022 · PreprintMicrobiology

Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its non-pathogenic close relatives

E. A. Hatmaker, M. Rangel-Grimaldo, H. A. Raja, S. L. Knowles, H. Pourhadi, K. Fuller, E. M. Adams, J. D. Lightfoot, R. Bastos, G. H. Goldman, N. H. Oberlies, A. Rokas

This study compares genomic and phenotypic traits of Aspergillus flavus and its non-pathogenic relatives to understand pathogenicity evolution.

bioRxiv · Jul 12, 2022 · PreprintEvolutionary Biology

Secondary metabolites produced during Aspergillus fumigatus and Pseudomonas aeruginosa biofilm formation

R. Bastos, D. Akiyama, T. F. dos Reis, A. C. Colabardini, R. S. Luperini, P. A. de Castro, R. L. Baldini, T. Pacheco Fill, G. H. Goldman

This study identifies secondary metabolites produced by Aspergillus fumigatus and Pseudomonas aeruginosa during biofilm formation in normoxia and hypoxia, revealing differences in metabolite secretion between monoculture and co-culture.

bioRxiv · Apr 25, 2022Microbiology

Screening of chemical libraries for new antifungal drugs against Aspergillus fumigatus reveals the potential mechanism of action of miltefosine

T. F. dos Reis, M. A. C. Horta, A. C. Colabardini, C. M. Fernandes, L. P. Silva, R. Bastos, M. V. L. Fonseca, F. Wang, C. Martins, M. Rodrigues, C. Silva Pereira, M. Del Poeta, K. H. Wong, G. H. Goldman

This study screens 1,127 compounds against Aspergillus fumigatus, identifies miltefosine as fungicidal, and reveals RmiA as a transcription factor regulating sphingolipid biosynthesis involved in miltefosine resistance.

bioRxiv · May 19, 2021Microbiology