Uncovering the universality of self-replication in protein aggregation and its link to disease.
G. Meisl, C. K. Xu, J. D. Taylor, T. C. Michaels, A. Levin, D. E. Otzen, D. Klenerman, S. Matthews, S. Linse, M. Andreasen, T. Knowles
The paper investigates self-replication in protein aggregates, finding it common in both functional and pathological contexts, with disease-related aggregates replicating faster than biological ones.
bioRxiv · Jun 8, 2022Biophysics