Author

J. D. Valgardson

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. A. Johnson· 1 shared H. M. Kodama· 1 shared I. M. Piper· 1 shared J. E. Svendsen· 1 shared J. F. Amacher· 1 shared J. M. Antos· 1 shared K. Johnston· 1 shared K. L. Hvorecny· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

D. A. Johnson

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1 paper

Recent·Most cited

A second specificity-determining loop in Class A sortases: Biochemical characterization of natural sequence variation in chimeric SrtA enzymes

I. M. Piper, S. A. Struyvenberg, J. D. Valgardson, D. A. Johnson, M. Gao, K. Johnston, J. E. Svendsen, H. M. Kodama, K. L. Hvorecny, J. M. Antos, J. F. Amacher

The paper identifies a conserved loop in Class A sortases that influences substrate specificity and demonstrates how engineered chimeric enzymes can expand substrate tolerance.

bioRxiv · Mar 27, 2021Biochemistry