The oral pathogen Porphyromonas gingivalis resists the antimicrobial peptide LGL13K and evades the D-enantiomer by synonymous mutations in hagA
S.-U. Gorr, R. Chen, J. E. Abrahante, P. B. M. Joyce
This study identifies synonymous mutations in hagA that confer resistance to DGL13K in P. gingivalis by altering mRNA structure and reducing HagA expression, without affecting mRNA levels.
bioRxiv · Sep 7, 2023 · PreprintMicrobiology