Author

J. E. Saffitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

S. P. Chelko· 2 shared A. Asimaki· 1 shared A. Barnes· 1 shared A. Tafuni· 1 shared C. Bueno-Beti· 1 shared E. Field· 1 shared E. N. Cannon· 1 shared I. K. Heenan· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPathology

S. P. Chelko

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2 papers

Recent·Most cited

Innate Immune Signaling in Hearts and Buccal Mucosa Cells of Patients with Arrhythmogenic Cardiomyopathy

C. Bueno-Beti, A. Tafuni, S. P. Chelko, M. N. Sheppard, E. Field, J. Tollit, I. K. Heenan, A. Barnes, M. R. Taylor, L. Mestroni, J. P. Kaski, J. E. Saffitz, A. Asimaki

This study finds persistent NFκB signaling in cardiac myocytes and increased CCR2-expressing cells in arrhythmogenic cardiomyopathy patients, with similar findings in buccal mucosa cells from young subjects with disease alleles.

bioRxiv · Jul 25, 2023 · PreprintPathology

Mechanisms of Innate Immune Injury in Arrhythmogenic Cardiomyopathy

S. P. Chelko, V. Penna, M. Engel, M. Landim-Vieira, E. N. Cannon, K. Lavine, J. E. Saffitz

This study identifies NFκB signaling in cardiac myocytes as a driver of myocardial injury and arrhythmias in a mouse model of arrhythmogenic cardiomyopathy.

bioRxiv · Jul 12, 2023 · PreprintImmunology