Cryo-EM structure of the Hedgehog release protein Dispatched
F. Cannac, C. Qi, J. Falschlunger, G. Hausmann, K. Basler, V. M. Korkhov
This study presents the cryo-EM structure of Drosophila Dispatched, revealing its open conformation and unique Hh-binding mode, suggesting a receptor-chaperone role in Hedgehog release.
bioRxiv · Jul 18, 2019Biochemistry