Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
A. Antanasijevic, L. M. Sewall, C. A. Cottrell, D. G. Carnathan, L. E. Jimenez, J. T. Ngo, J. B. Silverman, B. Groschel, E. Georgeson, J. Bhiman, R. Bastidas, C. LaBranche, J. D. Allen, J. Copps, H. R. Perrett, , A. B. Ward
The paper uses cryoEM to analyze polyclonal antibody responses to HIV Env immunogens in rhesus macaques, revealing structural differences in antibody binding and immunogenicity of engineered mutations and glycan sites.
bioRxiv · Jan 28, 2021Immunology