Author

J. Flax

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

J. L. McGrath· 3 shared K. Lucas· 2 shared M. Dehghani· 2 shared B. Engelhardt· 1 shared B. H. Singer· 1 shared G. Hussey· 1 shared H. Nishihara· 1 shared K. Chen· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersBioengineering

J. L. McGrath

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Author profile →

4 papers

Recent·Most cited

Rapid Assessment of Biomarkers on Single Extracellular Vesicles Using 'Catch and Display' on Ultrathin Nanoporous Silicon Nitride Membranes

S. N. Walker, K. Lucas, M. J. Dewey, S. Badylak, G. Hussey, J. Flax, J. L. McGrath

This paper introduces CAD-LB, a microfluidic technique for rapid EV biomarker assessment, validated on nanoparticles, purified EVs, and clinical plasma samples.

bioRxiv · Apr 29, 2024Bioengineering

The Modular μSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro

M. C. McCloskey, P. Kasap, S. D. Ahmad, S.-H. Su, K. Chen, M. Mansouri, N. Ramesh, H. Nishihara, Y. Belyaev, V. V. Abhyankar, S. Begolo, B. H. Singer, K. F. Webb, K. Kurabayashi, J. Flax, , J. L. McGrath

The paper introduces a modular, mass-produced tissue chip platform for barrier tissue models, validated for blood-brain barrier studies and reconfigurable for other applications.

bioRxiv · Mar 28, 2022Bioengineering

Tangential flow microfluidics for the capture and release of nanoparticles and extracellular vesicles on conventional and ultrathin membranes

M. Dehghani, K. Lucas, J. Flax, J. L. McGrath, T. Gaborski

This study introduces tangential flow for analyte capture (TFAC) to purify nanoparticles and EVs using ultrathin membranes, showing higher efficiency and lower pressure requirements compared to conventional methods.

bioRxiv · Jun 19, 2019Bioengineering

Exosome labeling by lipophilic dye PKH26 results in significant increase in vesicle size

M. Dehghani, S. M. Gulvin, J. Flax, T. R. Gaborski

This study shows that PKH26 labeling increases exosome size, potentially affecting their biodistribution and cellular uptake, and suggests protein binding dyes are more reliable.

bioRxiv · Jun 18, 2019Biochemistry