M. J. Dewey

Generative design approach to combine architected Voronoi foams with porous collagen scaffolds to create a tunable composite biomaterial

This paper develops a generative design method to create tunable composite biomaterials by combining Voronoi foams with collagen scaffolds for better mechanical performance and conformal fitting in bone defect repair.

Soluble extracts from amnion and chorion membranes improve hMSC osteogenic response in a mineralized collagen scaffold

This study shows that adding soluble extracts from amnion and chorion membranes to mineralized collagen scaffolds enhances hMSC osteogenic activity and mineral deposition.

Evaluation of P. aeruginosa attachment on mineralized collagen scaffolds and addition of manuka honey to increase mesenchymal stem cell osteogenesis

This study evaluates how manuka honey affects bacterial colonization and osteogenesis of mesenchymal stem cells in mineralized collagen scaffolds.

Beta-Catenin Limits Osteogenesis on Regenerative Materials in a Stiffness-Dependent Manner

This study shows that beta-catenin limits osteogenesis on stiff nanoparticulate mineralized collagen glycosaminoglycan scaffolds by modulating Wnt and mechanotransduction pathways.

Repair of critical-size porcine craniofacial bone defects using a collagen-polycaprolactone composite biomaterial

This study evaluates a collagen-polycaprolactone composite for repairing large porcine craniofacial bone defects, showing limited bone regeneration and highlighting areas for improvement.

Glycosaminoglycan content of a mineralized collagen scaffold promotes mesenchymal stem cell secretion of factors to modulate angiogenesis and monocyte differentiation

Inclusion of a 3D-printed Hyperelastic bone mesh improves mechanical and osteogenic performance of a mineralized collagen scaffold

This study shows that adding a 3D-printed Hyperelastic Bone mesh to a mineralized collagen scaffold improves mechanical strength and osteogenic performance in bone regeneration.

Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling

This study shows that increasing stiffness of MC-GAG scaffolds enhances osteogenesis through YAP/TAZ and Wnt signaling, while BMPR signaling is independent of mechanical cues.

Anisotropic mineralized collagen scaffolds accelerate osteogenic response in a glycosaminoglycan-dependent fashion

This study shows anisotropic mineralized collagen scaffolds enhance osteogenic response in a glycosaminoglycan-dependent manner by improving bone mineral synthesis.