Author

J. G. Pelton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

N. R. Latorraca· 2 shared S. Marqusee· 2 shared A. J. Velasquez-Mao· 1 shared B. C. Maguire· 1 shared B. Lam· 1 shared D. Karandur· 1 shared D. Lee· 1 shared D. Wemmer· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

N. R. Latorraca

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Quantitative imaging of gene therapy delivery vehicles using CEST-NMR/MRI

B. Lam, M. Velasquez, A. J. Velasquez-Mao, K. Godines, W. AlGhuraibawi, M. Wendland, J. G. Pelton, M. Vandsburger

This study uses CEST-NMR/MRI to quantify AAV vector delivery by measuring CEST contrast from viral capsids, showing strong correlations with capsid density and viral titer.

bioRxiv · Nov 9, 2022 · PreprintBioengineering

A Saturation-Mutagenesis Analysis of the Interplay Between Stability and Activation in Ras

F. Hidalgo, L. M. Nocka, N. H. Shah, K. Gorday, N. R. Latorraca, P. Bandaru, S. Templeton, D. Lee, D. Karandur, J. G. Pelton, S. Marqusee, D. Wemmer, J. Kuriyan

This study shows that cancer hotspot mutations in Ras activate it regardless of stability, while non-hotspot mutations can be activating or deleterious depending on stability.

bioRxiv · Jan 6, 2022Biophysics

Mechanistic basis for ubiquitin modulation of a protein energy landscape

E. C. Carroll, N. R. Latorraca, J. M. Lindner, B. C. Maguire, J. G. Pelton, S. Marqusee

This study investigates how ubiquitination at different sites affects the energy landscape of a model protein, revealing distinct thermodynamic mechanisms for destabilization and protection.

bioRxiv · Dec 6, 2020Biophysics