Author

K. Gorday

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Kuriyan· 2 shared D. Karandur· 1 shared D. Lee· 1 shared D. Wemmer· 1 shared F. Hidalgo· 1 shared J. G. Pelton· 1 shared K. Marcus· 1 shared L. M. Nocka· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

J. Kuriyan

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2 papers

Recent·Most cited

A Saturation-Mutagenesis Analysis of the Interplay Between Stability and Activation in Ras

F. Hidalgo, L. M. Nocka, N. H. Shah, K. Gorday, N. R. Latorraca, P. Bandaru, S. Templeton, D. Lee, D. Karandur, J. G. Pelton, S. Marqusee, D. Wemmer, J. Kuriyan

This study shows that cancer hotspot mutations in Ras activate it regardless of stability, while non-hotspot mutations can be activating or deleterious depending on stability.

bioRxiv · Jan 6, 2022Biophysics

Allosteric communication in DNA polymerase clamp loaders relies on a critical hydrogen-bonded junction

S. Subramanian, K. Gorday, K. Marcus, M. R. Orellana, P. Ren, X. R. Luo, M. E. O'Donnell, J. Kuriyan

The paper identifies a hydrogen-bonded junction in DNA polymerase clamp loaders that is critical for allosteric communication, preserved across diverse AAA+ ATPases.

bioRxiv · Dec 31, 2020Biophysics