Recapitulating evolutionary divergence in a single regulatory element causes expression changes of the lens gene Tdrd7
J. G. Roscito, K. Subramanian, R. Naumann, M. Sarov, A. Shevchenko, A. Bogdanova, T. Kurth, L. Forster, M. Kreysing, M. Hiller
The paper investigates how mutations in a regulatory element upstream of Tdrd7 affect lens development by replacing the mouse sequence with the blind mole rat sequence in mice.
bioRxiv · Mar 22, 2020Evolutionary Biology