Author

R. Naumann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:mouse· 5 Approach:experimental assay· 4 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Bogdanova· 1 shared A. Honigmann· 1 shared A. Krueger· 1 shared A. Platz· 1 shared A. Shevchenko· 1 shared A. Vanyushkina· 1 shared B. Ludwig· 1 shared B. S. Sundarasetty· 1 shared

Activity by Year

2018-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEvolutionary Biology

A. Bogdanova

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Reduced purine biosynthesis in humans after their divergence from Neandertals

V. Stepanova, K. E. Moczulska, G. N. Vacano, X.-c. Ju, S. Riesenberg, D. Macak, T. Maricic, L. Dombrowski, M. Schörnig, K. Anastassiadis, O. Baker, R. Naumann, E. E. Khrameeva, A. Vanyushkina, E. Stekolschikova, , S. Pääbo

The paper compares metabolomes across humans, chimpanzees, and macaques to identify reduced purine biosynthesis in humans, linked to an amino acid substitution in adenylosuccinate lyase.

bioRxiv · May 11, 2020Evolutionary Biology

Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7.

E. Coppin, B. S. Sundarasetty, S. Rahmig, J. Blume, N. A. Verheyden, F. Bahlmann, S. Ravens, U. Schubert, J. Schmid, S. Ludwig, C. von Kaisenberg, A. Platz, R. Naumann, B. Ludwig, I. Prinz, , A. Krueger

This study creates a humanized mouse model with enhanced T cell differentiation by expressing human IL-7 in specific tissues, leading to increased functional T cells without lymphoproliferation.

bioRxiv · Apr 24, 2020Immunology

Recapitulating evolutionary divergence in a single regulatory element causes expression changes of the lens gene Tdrd7

J. G. Roscito, K. Subramanian, R. Naumann, M. Sarov, A. Shevchenko, A. Bogdanova, T. Kurth, L. Forster, M. Kreysing, M. Hiller

The paper investigates how mutations in a regulatory element upstream of Tdrd7 affect lens development by replacing the mouse sequence with the blind mole rat sequence in mice.

bioRxiv · Mar 22, 2020Evolutionary Biology

Optimization of mouse embryonic stem cell culture for organoid and chimeric mice production.

C. Martin-Lemaitre, Y. Alcheikh, R. Naumann, A. Honigmann

This study compares four mESC culture conditions, finding that CHIR99021/LIF suspension culture best balances effort, pluripotency, and homogeneity for organoid and chimeric mouse production.

bioRxiv · Mar 13, 2020 · PreprintCell Biology

An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice

J. L. P. Castro, M. N. Yancoskie, M. Marchini, S. Belohlavy, M. Kucka, W. H. Beluch, R. Naumann, I. Skuplik, J. Cobb, N. H. Barton, C. Rolian, Y. F. Chan

This study analyzes the genomic changes in mice selectively bred for longer limbs, identifying polygenic adaptation and major-effect loci linked to bone growth regulation.

bioRxiv · Aug 19, 2018Evolutionary Biology