Evolution and adaptation of Pseudomonas aeruginosa in the paranasal sinuses of people with cystic fibrosis
C. R. Armbruster, C. W. Marshall, J. A. Melvin, A. C. Zemke, A. I. Garber, J. Moore, K. Li, P. F. Zamora, I. L. Fritz, C. D. Manko, M. L. Weaver, J. Gaston, A. Morris, B. Methe, S. E. Lee, , J. M. Bomberger
This study identifies three evolutionary genetic routes of Pseudomonas aeruginosa adaptation in the sinuses of people with cystic fibrosis, suggesting sinuses may be an early site of pathoadaptation before lung infections.
bioRxiv · Oct 29, 2020 · PreprintMicrobiology