Helicobacter pylori accelerates KRAS-dependent gastric dysplasia
V. P. O'Brien, A. Koehne, J. Dubrulle, A. Rodriguez, C. Leverich, P. Kong, J. Campbell, R. Pierce, J. Goldenring, E. Choi, N. Salama
This study shows that Helicobacter pylori infection accelerates KRAS-driven gastric dysplasia in mice by promoting inflammation, altering gene expression, and increasing proliferation of preneoplastic glands.
bioRxiv · Oct 6, 2020Cancer Biology