Author

A. Koehne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. M. Houghton· 1 shared A. Rodriguez· 1 shared A. Soerens· 1 shared A. Woodward-Davis· 1 shared B. Freie· 1 shared C. Leverich· 1 shared C. Teague· 1 shared D. P. MacPherson· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. M. Houghton

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Author profile →

3 papers

Recent·Most cited

Loss of MGA mediated Polycomb repression promotes tumor progression and invasiveness

H. Mathsyaraja, J. Catchpole, E. Eastwood, E. Babaeva, M. J. Geuenich, P.-F. Cheng, B. Freie, J. L. Ayers, M. Yu, N. Wu, K. R. Poudel, A. Koehne, W. Grady, A. M. Houghton, Y. Shiio, , R. N. Eisenman

This study shows that loss of MGA promotes tumor growth and invasiveness by de-repressing Polycomb targets in lung and colon cancers.

eLife · Jul 8, 2021Peer-reviewedCancer Biology

Helicobacter pylori accelerates KRAS-dependent gastric dysplasia

V. P. O'Brien, A. Koehne, J. Dubrulle, A. Rodriguez, C. Leverich, P. Kong, J. Campbell, R. Pierce, J. Goldenring, E. Choi, N. Salama

This study shows that Helicobacter pylori infection accelerates KRAS-driven gastric dysplasia in mice by promoting inflammation, altering gene expression, and increasing proliferation of preneoplastic glands.

bioRxiv · Oct 6, 2020Cancer Biology

Cervicovaginal tissue residence imprints a distinct differentiation program upon memory CD8 T cells

V. Dave, E. F. Cardozo Ojeda, F. Mair, J. Erickson, A. Woodward-Davis, A. Soerens, A. Koehne, J. Czartoski, C. Teague, N. Potchen, S. Oberle, D. Zehn, J. Schiffer, J. M. Lund, M. Prlic

The paper shows that residence in cervicovaginal tissue shapes CD8 T cell phenotype and function, leading to reduced local immunity and impaired viral control upon secondary challenge.

bioRxiv · Apr 23, 2020 · PreprintImmunology