Author

J. Gonzalez-Molina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

G. Kokaraki· 3 shared J. W. Carlson· 3 shared K. Lehti· 3 shared L. Moyano-Galceran· 2 shared O. Gultekin· 2 shared A. Bjorkoy· 1 shared A. Isaksson· 1 shared B. Rathod· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

G. Kokaraki

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3 papers

Recent·Most cited

YAP and collagen remodelling support cell proliferation and tumour aggressiveness in uterine leiomyosarcoma

J. Gonzalez-Molina, P. Hahn, R. M. Falcao, O. Gultekin, G. Kokaraki, V. Zanfagnin, T. B. Petta, K. Lehti, J. W. Carlson

This study shows that YAP and collagen remodelling enable LMS cell proliferation and aggressiveness by adapting to low collagen and soft environments.

bioRxiv · Jun 27, 2022 · PreprintCancer Biology

Mechanical confinement and DDR1 signalling synergise to regulate collagen-induced apoptosis in rhabdomyosarcoma cells

J. Gonzalez-Molina, K. M. Kirchhof, B. Rathod, L. Moyano-Galceran, M. Calvo-Noriega, G. Kokaraki, A. Bjorkoy, M. Ehnman, J. W. Carlson, K. Lehti

This study shows that dense collagen-rich environments induce apoptosis in rhabdomyosarcoma cells via DDR1 and TRPV4 signaling, explaining their preference for low collagen microenvironments.

bioRxiv · Apr 26, 2022 · PreprintCancer Biology

Regulatory FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation

O. Gultekin, J. Gonzalez-Molina, E. Hardell, L. Moyano-Galceran, N. Mitsios, J. Mulder, G. Kokaraki, A. Isaksson, D. Sarhan, K. Lehti, J. W. Carlson

This study identifies immune signatures in uterine sarcomas, finding that FOXP3+ regulatory T cells and M1-like macrophages correlate with better prognosis.

bioRxiv · Mar 26, 2021Cancer Biology