Author

O. Gultekin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. Lehti· 3 shared D. Sarhan· 2 shared G. Kokaraki· 2 shared J. Gonzalez-Molina· 2 shared J. W. Carlson· 2 shared A. Isaksson· 1 shared A. R. Furones· 1 shared E. Hardell· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

K. Lehti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enhanced NK cell proficiency in solid tumors through antigen-specific memory via NKG2C/A-HLA-E/ABC recruited to tumors by CXCR2

Y. Sun, A. R. Furones, O. Gultekin, S. Khare, S. Y. Neo, W. Shi, L. M. Galceran, K.-P. Lam, R. DasGupta, J. Fuxe, S. Salehi, K. Lehti, D. Sarhan

This study shows that antigen-specific memory NK cells can be generated in ovarian cancer, enhancing their cytotoxicity and tumor reactivity through NKG2C/A-HLA-E/ABC interactions and CXCR2-mediated migration.

bioRxiv · Mar 28, 2024 · PreprintImmunology

YAP and collagen remodelling support cell proliferation and tumour aggressiveness in uterine leiomyosarcoma

J. Gonzalez-Molina, P. Hahn, R. M. Falcao, O. Gultekin, G. Kokaraki, V. Zanfagnin, T. B. Petta, K. Lehti, J. W. Carlson

This study shows that YAP and collagen remodelling enable LMS cell proliferation and aggressiveness by adapting to low collagen and soft environments.

bioRxiv · Jun 27, 2022 · PreprintCancer Biology

Regulatory FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation

O. Gultekin, J. Gonzalez-Molina, E. Hardell, L. Moyano-Galceran, N. Mitsios, J. Mulder, G. Kokaraki, A. Isaksson, D. Sarhan, K. Lehti, J. W. Carlson

This study identifies immune signatures in uterine sarcomas, finding that FOXP3+ regulatory T cells and M1-like macrophages correlate with better prognosis.

bioRxiv · Mar 26, 2021Cancer Biology