Targeting a shared neoepitope derived from non-canonical translation of c-MYC oncogene in cancer cells
Estelle Baulu, A. Bolon, Ema Etchegaray, Félix Raimundo, Audrey Merienne, Juliette Martin, J. Grandsire, T. Richard, Laurie Tonon, C. Dubois, Yann Estornes, Rasha E. Boulos, Olivier Tabone, Paola Bonaventura, Adeline Page, , Stéphane Depil
The paper identifies a shared neoepitope from non-canonical c-MYC translation in cancer cells that activates T cells to kill tumors without harming normal cells.
bioRxiv · May 23, 2024 · PreprintImmunology