C. Dubois

Targeting a shared neoepitope derived from non-canonical translation of c-MYC oncogene in cancer cells

The paper identifies a shared neoepitope from non-canonical c-MYC translation in cancer cells that activates T cells to kill tumors without harming normal cells.

Transient hypoxia followed by progressive reoxygenation is required for efficient skeletal muscle repair through Rev-ERBalpha modulation

This study shows that transient hypoxia followed by reoxygenation is essential for skeletal muscle repair, mediated by Rev-ERBalpha regulation of myogenesis.

Caspase cleavage of Influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production

This study shows that caspase cleavage of the Influenza A virus M2 protein disrupts its interaction with LC3, reducing virion production.

Consequences of platelet-educated cancer cells on the expression of inflammatory and metastatic glycoproteins.

This study shows platelets can educate cancer cells to alter their expression of inflammatory and metastatic glycoproteins, suggesting new therapeutic targets for cancer treatment.

ADP-dependent platelet activation is required for thrombus formation during a long-distance flight

This study shows that ADP-dependent platelet activation contributes to DVT during flight, and P2RY12 inhibitors may prevent it.

A thrombus is formed by a gradient of platelet activation and procoagulant endothelium

The paper uses computational biology to analyze thrombus formation, showing platelet activation gradients and endothelial role in coagulation.

Targeting BTN2A1 enhances Vγ9Vδ2 T cell effector functions and triggers tumor cells pyroptosis

Maternal age affects equine Day 8 embryo gene expression both in trophoblast and inner cell mass

This study examines how maternal age impacts gene expression in equine Day 8 embryos, identifying differences in mitochondrial and metabolic pathways in both trophoblast and inner cell mass.

A broad mutational target explains an evolutionary trend

The paper identifies a broad mutational target as the cause of high mutational variance in the P3.p cell fate among Caenorhabditis nematodes, explaining an evolutionary trend.