Benjamin Gillet

Spatio-temporal control of myoblast identity drives muscle diversity in the Drosophila leg

This study identifies how epithelial morphogens guide stepwise mesodermal specification to generate muscle diversity in Drosophila leg development.

Ecdysone-mediated intestinal growth contributes to microbiota-driven developmental plasticity under malnutrition

The paper shows that Lactiplantibacillus plantarum enhances midgut growth in Drosophila larvae under malnutrition via Ecdysone signaling, revealing a microbiota-driven mechanism for developmental plasticity.

Characterizing drug activity with sensitive interactomes in human living cells

The paper introduces a method to identify drug-sensitive protein-protein interactions in live cells using ERK1 as a case study, showing how inhibitory molecules affect these interactions.

Juvenile protein restriction compresses sexual dimorphism in mice

This study shows that juvenile protein restriction in mice reduces sexual dimorphism by affecting somatic growth, energy metabolism, and hepatic molecular identity, with distinct adaptations in reproductive development.

LAM/TREM2+ macrophages release extracellular vesicles and extracellular lipid droplets which modulate the phenotype of recipient macrophages and homeostasis of skeletal muscle cells

Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues

This study uses long-read RNA-seq to identify and quantify transposable element transcripts at the copy level in Drosophila germline tissues, revealing differences in their transcriptional landscape between testes and ovaries.

Targeting a shared neoepitope derived from non-canonical translation of c-MYC oncogene in cancer cells

The paper identifies a shared neoepitope from non-canonical c-MYC translation in cancer cells that activates T cells to kill tumors without harming normal cells.

AtVPS13M1 is involved in lipid remodeling in low phosphate and is located at the mitochondria surface in plants

This study identifies AtVPS13M1 as a lipid transporter in Arabidopsis thaliana that affects phospholipid degradation during phosphate starvation and localizes to mitochondria.

Dual-topology of collagen XV and tenascin C acts in concert to guide and shape developing motor axons

The paper identifies Collagen XV-B and Tenascin C as ECM components guiding motor axon growth through their dual topology and stiffness in zebrafish.

Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.

The paper examines gene expression coordination between host and endosymbiont during the life cycle of the cereal weevil, identifying shared regulatory functions involved in symbiosis dynamics.

A live cell protein complementation assay for ORFeome-wide probing of human HOX interactomes

The paper introduces Cell-PCA, a live cell protein complementation assay, to probe human HOX interactomes, revealing novel cofactors and molecular properties.

Distinct gene expression dynamics in developing and regenerating limbs

This study compares gene expression dynamics during leg development and regeneration in Parhyale hawaiensis, finding distinct temporal patterns despite shared gene sets.

The transposable element-rich genome of the cereal pest Sitophilus oryzae

The paper presents the genome of Sitophilus oryzae, revealing high transposable element content and host-symbiont metabolic interactions.

Nomadic Lifestyle of Lactobacillus plantarum Revealed by Comparative Genomics of 54 strains Isolated from Different Niches

This study analyzes 54 Lactobacillus plantarum genomes to show that their genome evolution is not tied to specific environmental niches, suggesting a nomadic lifestyle.