Author

J. Grosser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Muik· 2 shared A. Toker· 2 shared B. G. Lui· 2 shared D. P. Cameron· 2 shared K. Grikscheit· 2 shared L. Baranello· 2 shared M. Bacher· 2 shared N. Kohmer· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

A. Muik

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Efficient generation of transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein

H. Su, y. wang, J. Xu, A. Omar, J. Grosser, M. Calovic, L. Zhang, C. Vakulskas, N. Wang

This study generates transgene-free canker-resistant citrus plants using Cas12a/crRNA RNP editing, achieving high mutation rates and regulatory approval.

bioRxiv · Feb 12, 2023 · PreprintBioengineering

Co-inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills pancreatic cancer via readthrough transcription

D. P. Cameron, J. Grosser, S. Ladigan, V. Kuzin, E. Iliopoulou, A. Wiegard, H. Benredjem, S. T. Liffers, S. Lueong, P. F. Cheung, D. Vangala, M. Pohl, R. Viebahn, C. Teschendorf, H. Wolters, , L. Baranello

The paper shows that combining TOP1 and BRD4 inhibitors selectively kills pancreatic cancer cells by inducing readthrough transcription, without harming normal cells.

bioRxiv · Feb 10, 2023Cancer Biology

Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T-cell recognition epitopes

A. Muik, B. G. Lui, H. Diao, Y. Fu, M. Bacher, A. Toker, J. Grosser, O. Ozhelvaci, K. Grikscheit, S. Hoehl, N. Kohmer, Y. Lustig, G. Regev-Yochay, S. Ciesek, K. Beguir, , U. Sahin

The paper examines how Omicron sublineages evade neutralizing antibodies but retain T-cell epitopes, suggesting T-cell immunity remains effective against these variants.

bioRxiv · Dec 15, 2022 · PreprintImmunology

Exposure to BA.4/BA.5 Spike glycoprotein drives pan-Omicron neutralization in vaccine-experienced humans and mice

A. Muik, B. G. Lui, M. Bacher, A.-K. Wallisch, A. Toker, C. I. C. Couto, A. Gueler, V. Mampilli, G. J. Schmitt, J. Mottl, T. Ziegenhals, S. Fesser, J. Reinholz, F. Wernig, K.-G. Schraut, , U. Sahin

This study shows that exposure to BA.4/BA.5 spike glycoprotein enhances neutralizing antibody breadth against Omicron variants in vaccinated humans and mice.

bioRxiv · Sep 21, 2022 · PreprintImmunology

The assisting role of Polη in transcription facilitates formation of damage-induced cohesion

L. Ström, P.-S. Wu, D. P. Cameron, J. Grosser, L. Baranello

This paper shows that Polη assists transcription, which facilitates damage-induced cohesion in yeast.

bioRxiv · Dec 20, 2020 · PreprintCell Biology