Author

J. Guha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Kang· 1 shared B. L. Kelsall· 1 shared E. Claudio· 1 shared H. Wang· 1 shared N. R. Redekar· 1 shared P. M. Murphy· 1 shared R. Chari· 1 shared U. Siebenlist· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

B. Kang

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2 papers

Recent·Most cited

NF kappa B Regulator Bcl3 Controls Development and Function of Classical Dendritic Cells in Toxoplasma gondii

J. Guha, B. Kang, E. Claudio, N. R. Redekar, H. Wang, B. L. Kelsall, U. Siebenlist, P. M. Murphy

This study shows that Bcl3 in classical dendritic cells is critical for host protection against Toxoplasma gondii by regulating antigen presentation and T cell responses.

bioRxiv · Apr 7, 2022 · PreprintImmunology

Disc Large Homolog 1 is critical for early microcluster formation and activation in human T cells

J. Guha, R. Chari

This study shows DLG1 is essential for early TCR-microcluster formation and T cell activation by bridging TCR-zeta and ZAP70 while blocking SHP1 binding.

bioRxiv · May 24, 2021Immunology