ER stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress
N. Ho, H. Wu, J. Xu, J. H. Koh, W. S. Yap, W. W. B. Goh, S. C. Chong, S. Taubert, G. Thibault
The paper identifies a lipid bilayer stress sensing mechanism in the UPR transducer Ire1 and shows it activates divergent transcriptional programs in yeast and C. elegans.
bioRxiv · Sep 18, 2019Cell Biology