NHR-49/PPAR-α and HLH-30/TFEB promote C. elegans host defense via a flavin-containing monooxygenase
K. A. Wani, D. Goswamy, S. Taubert, R. Ratnappan, A. Ghazi, J. E. Irazoqui
This study identifies NHR-49/PPAR-α and HLH-30/TFEB as regulators of an infection-specific host response in C. elegans, revealing FMOs as innate immunity effectors.
bioRxiv · Sep 3, 2020Microbiology