Targeted phosphoproteomics of the Ras signaling network reveal regulatory mechanisms mediated by oncogenic KRAS
A. Urisman, T. L. Yuan, M. Trinidad, J. H. Morris, S. Afghani, J. A. Oses-Prieto, C. D. Ritchie, M. S. Zahari, C. H. Benes, A. L. Burlingame, F. McCormick
This study uses targeted phosphoproteomics to analyze KRAS signaling network regulation in lung cancer cells, identifying unique phosphorylation changes and their roles in transcriptional silencing.
bioRxiv · Jul 9, 2019 · PreprintCancer Biology