Author

J. H.-C. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

J. Zhang· 3 shared D. Nie· 2 shared F. Li· 2 shared K. Onishi· 2 shared A. McDowell· 1 shared G. Zhao· 1 shared K. M. Williamson· 1 shared K. Williamson· 1 shared

Activity by Year

2019-2021 · peak 1/yr

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10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

J. Zhang

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3 papers

Recent·Most cited

Platelet HMGB1 in Platelet-Rich Plasma Promotes Tendon Wound Healing

J. Zhang, F. Li, T. Augi, K. M. Williamson, K. Onishi, M. V. Hogan, M. D. Neal, J. H.-C. Wang

This study shows that platelet HMGB1 in PRP enhances tendon healing in mice, with PRP from GFP mice promoting faster healing and better tissue organization compared to PRP from HMGB1 KO mice.

bioRxiv · Apr 22, 2021Cell Biology

Moderate and intensive mechanical loading differentially modulate the phenotype of tendon stem/progenitor cells in vivo

J. Zhang, D. Nie, K. Williamson, A. McDowell, M. Hogan, J. H.-C. Wang

This study shows that moderate treadmill running maintains tendon homeostasis by promoting TSC differentiation into tenocytes, while intensive treadmill running induces tendinopathy by causing TSCs to differentiate into non-tenocyte cells.

bioRxiv · Nov 9, 2020Cell Biology

HMGB1 mediates the development of tendinopathy due to mechanical overloading

G. Zhao, J. Zhang, D. Nie, Y. Zhou, F. Li, K. Onishi, J. H.-C. Wang

This study shows that HMGB1 release in response to mechanical overloading causes inflammation and tendinopathy in mice, which can be blocked by glycyrrhizin.

bioRxiv · Aug 29, 2019Cell Biology