Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination
K. Mueller, M. P. Gibbins, M. Roberts, A. Reyes-Sandoval, A. Hill, S. Draper, K. Matuschewski, O. Silvie, J. Hafalla
This study shows that poor immunogenicity of EEF antigens does not prevent their susceptibility to CD8+ T cell killing, challenging the assumption that immunogenicity is a key criterion for vaccine development.
bioRxiv · Sep 3, 2020Immunology