Author

S. Draper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Jamwal· 2 shared M. K. Higgins· 2 shared A. E. Armitage· 1 shared A. E. Preston· 1 shared A. Hill· 1 shared A. Reyes-Sandoval· 1 shared B. Fakler· 1 shared B. Farrell· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Jamwal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cellular iron governs the host response to malaria

S. K. Wideman, J. N. Frost, F. C. Richter, C. Naylor, J. M. Lopes, N. Viveiros, M. R. Teh, A. E. Preston, N. White, S. Yusuf, S. Draper, A. E. Armitage, T. L. Duarte, H. Drakesmith

This study shows that host cell iron scarcity inhibits immune response but reduces liver damage during malaria infection.

bioRxiv · Feb 5, 2023Immunology

Structure of the PfRCR complex which bridges the malaria parasite and erythrocyte during invasion

B. Farrell, N. Alam, M. Hart, A. Jamwal, R. Ragotte, H. Walters-Morgan, S. Draper, E. Knuepfer, M. K. Higgins

This paper determines the structure of the PfRCR complex using cryogenic-electron microscopy, revealing its modular architecture and interaction with erythrocyte receptors, which informs vaccine design.

bioRxiv · Jan 30, 2023Microbiology

Erythrocyte invasion-neutralising antibodies prevent Plasmodium falciparum RH5 from binding to basigin-containing membrane protein complexes

A. Jamwal, C. Constantin, S. Henrich, W. Bildl, B. Fakler, S. Draper, U. Schulte, M. K. Higgins

The paper shows that PfRH5 binds to basigin-containing membrane complexes rather than isolated basigin, and effective antibodies block this interaction to inhibit parasite growth.

bioRxiv · Sep 23, 2022Microbiology

Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination

K. Mueller, M. P. Gibbins, M. Roberts, A. Reyes-Sandoval, A. Hill, S. Draper, K. Matuschewski, O. Silvie, J. Hafalla

This study shows that poor immunogenicity of EEF antigens does not prevent their susceptibility to CD8+ T cell killing, challenging the assumption that immunogenicity is a key criterion for vaccine development.

bioRxiv · Sep 3, 2020Immunology