G-quadruplex DNA structures mediate non-autonomous instruction of breast tumour microenvironments
P. Hunold, M. N. Hoehne, M. Kiljan, O. van Ray, J. Herter, G. S. Herter-Sprie, R. Haensel-Hertsch
The paper identifies G-quadruplex DNA structures in breast cancer that non-autonomously instruct macrophage transcriptomes and epigenomes, promoting immunosuppression in the tumor microenvironment.
bioRxiv · Jan 16, 2023 · PreprintCancer Biology