Author

J. Hougland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

A. Gregory-Flores· 1 shared B. J. Tunstall· 1 shared B. K. Mani· 1 shared D. M. Harvey· 1 shared E. Gardner· 1 shared E. R. Cleverdon· 1 shared E. R. Curtis· 1 shared F. Akhlaghi· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

A. Gregory-Flores

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Author profile →

2 papers

Recent·Most cited

A remarkably specific ligand reveals ghrelin O-acyltransferase interacts with extracellular peptides and exhibits unexpected cellular localization for a secretory pathway enzyme

M. B. Campana, T. R. Davis, E. R. Cleverdon, M. Bates, N. Krishnan, E. R. Curtis, M. D. Childs, M. R. Pierce, S. X. Novak, Y. Morales-Rodriguez, M. Sieburg, H. Hehnly, L. G. Luyt, J. Hougland

This study identifies a specific ligand that shows GOAT interacts with extracellular ghrelin and facilitates its internalization, revealing new insights into its catalytic mechanism and signaling role.

bioRxiv · Jun 1, 2021 · PreprintBiochemistry

Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical Investigations

M. Farokhnia, S. L. Deschaine, A. Gregory-Flores, L. J. Zallar, Z.-B. You, H. Sun, D. M. Harvey, R. C. N. Marchette, B. J. Tunstall, B. K. Mani, J. E. Moose, M. R. Lee, E. Gardner, F. Akhlaghi, M. Roberto, , L. Leggio

This study investigates how alcohol affects the ghrelin system in humans and rats, finding that ethanol reduces peripheral ghrelin levels without involving the ghrelin receptor or GOAT enzyme, and not proportionally to caloric intake.

bioRxiv · Jul 30, 2020 · PreprintPhysiology