Author

J. J. A. Saab

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Cancer Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. Muir· 1 shared C. R. Weber· 1 shared C. Sheehan· 1 shared K. F. Macleod· 1 shared L. N. Dzierozynski· 1 shared M. Oh· 1 shared P. B. Jonker· 1 shared R. N. Chen· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Muir

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1 paper

Recent·Most cited

Pancreatic tumors activate arginine biosynthesis to adapt to myeloid-driven amino acid stress

J. J. A. Saab, L. N. Dzierozynski, P. B. Jonker, Z. Zhu, R. N. Chen, M. Oh, C. Sheehan, K. F. Macleod, C. R. Weber, A. Muir

The paper develops a cell culture medium mimicking the PDAC tumor microenvironment and identifies arginine biosynthesis as a metabolic adaptation to myeloid-driven arginine starvation.

bioRxiv · Jun 21, 2022Cancer Biology