BiophysicsbioRxiv
Stability of local secondary structure determines selectivity of viral RNA chaperones
J. P. K. Bravo, A. Borodavka, A. Barth…·R. Tuma
This study compares the ability of viral RNA chaperones NSP2 and σNS to promote inter-segment RNA-RNA interactions, finding that NSP2's high affinity for structured RNAs and efficient helix disruption enable successful inter-segment association, while σNS lacks this capacity.
DOI 10.1093/nar/gky394