Multiple phase-variable mechanisms, including capsular polysaccharides, modify bacteriophage susceptibility in Bacteroides thetaiotaomicron
N. T. Porter, A. J. Hryckowian, B. D. Merrill, J. J. Fuentes, J. O. Gardner, R. W. P. Glowacki, S. Singh, R. D. Crawford, E. S. Snitkin, J. L. Sonnenburg, E. C. Martens
This study shows that capsular polysaccharides and other phase-variable cell surface structures in Bacteroides thetaiotaomicron influence bacteriophage susceptibility, enabling bacterial persistence through phase variation.
bioRxiv · Mar 26, 2020 · PreprintMicrobiology