Author

J. J. Miettinen

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. A. Heckman· 1 shared E. Gholizadeh· 1 shared F. Ianevski· 1 shared J. Saarela· 1 shared M. Jafari· 1 shared M. Manninen· 1 shared M. Mirzaie· 1 shared S. Miettinen· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

C. A. Heckman

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1 paper

Recent·Most cited

Cancer BiologybioRxivMay 25, 2023

Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling

M. Mirzaie, E. Gholizadeh, J. J. Miettinen…·M. Jafari

This paper identifies effective and low-toxicity drug combinations for AML using a bipartite network model and patient-derived data, finding ruxolitinib-ulixertinib and sapanisertib-LY3009120 as the most synergistic.

DOI 10.1038/s41389-024-00510-9

humanbulk RNA-seq

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